Principal Bioinformatics Scientist Job at F. Hoffmann-La Roche Ltd, Pleasanton, CA

M2YwV2dUbmdsL3MraStlcE5GNTcvbVlCQ3c9PQ==
  • F. Hoffmann-La Roche Ltd
  • Pleasanton, CA

Job Description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

We are seeking a talented and highly motivated Bioinformatics Scientist to support the development of Roche Diagnostics Molecular Assays that have a global impact on patient care. This role requires a broad understanding of assay development across diverse technologies, including NGS, Nanopore sequencing, and PCR. The successful candidate will collaborate closely with bioinformaticians, wet lab scientists, and external customers to design, implement, and maintain internal algorithms and tools for clinical diagnostic assay development.

The Opportunity:
  • Collaborate with multidisciplinary teams of molecular and computational biologists, as well as wet lab scientists, to design, optimize, and troubleshoot advanced high-throughput sequencing assays and workflows for clinical diagnostic applications.
  • Contribute bioinformatics expertise throughout the assay development lifecycle, including initial sequencing, validation, and production implementation, by developing and maintaining analytical tools and pipelines for processing diagnostic data from tumor, germline, and cell-free DNA samples.
  • Create, implement, and streamline bioinformatics tools and workflows in partnership with wet lab scientists to enhance assay development efficiency and data quality.
  • Provide hands-on troubleshooting to ensure data quality, integrity, and accessibility across the diagnostic workflow, while addressing the needs of internal and external stakeholders through scientific and business analyses.
  • Advocate for best practices in documenting, training, and scaling algorithms, tools, and workflows to ensure reproducibility and scalability.
  • Clearly communicate project outcomes and team progress across various teams and organizational functions to promote alignment and collaboration.

Who You Are:
  • You have a PhD or Master's degree in Bioinformatics, Computational Biology, Statistics, or a related field.
  • You have 6+ years of industry experience in clinical diagnostics or a related domain.
  • You have expertise in DNA/RNA sequencing data analysis and interpretation.
  • You are proficient in programming skills in R and/or Python, with experience working in a distributed Linux environment.
  • You are proficient in creating clear, insightful visualizations of complex biological data, with strong presentation skills to effectively communicate results to both technical and non-technical audiences.
  • You have a strong understanding of molecular biology principles and hands-on familiarity with next-generation sequencing laboratory processes. Able to work closely with bench scientists to troubleshoot experimental and workflow issues.
  • You are skilled in writing and maintaining bioinformatics workflows using workflow management systems such as Snakemake or Nextflow
  • You have demonstrated the ability to independently develop informatics solutions and contribute to scientific informatics initiatives.
  • You have a solid understanding of cancer biology and in vitro diagnostics (IVD).

Preferred Qualifications:
  • Proficiency in C++ or Java is a plus.

The expected salary range for this position is based on the primary location of Pleasanton, CA. 135,200-251,200. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.

This position also qualifies for the benefits detailed at the link provided below.

Benefits

Relocation benefits are available for this position.

Who we are

A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let's build a healthier future, together.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Job Tags

Full time, Local area, Relocation package,

Similar Jobs

MOVE Your Business

LinkedIn DM and Email Marketing Specialist Job at MOVE Your Business

 ...throughout the exit journey. On behalf of our client, we are seeking a detail-oriented and results-driven LinkedIn DM and Email Marketing Specialist to support our clients pipeline growth. The ideal candidate will be responsible for engaging EO/YPO/Vistage targets... 

Bristow Group

Helicopter Pilot at Bristow Group Job at Bristow Group

 ...continuously seeking top talent to join our team. Applications are now being accepted for VFR and IFR PICs, as well as IFR SIC helicopter pilots to provide support to the offshore oil & gas industry. All qualified applicants can submit an application and resume by applying to... 

Med Source Consultants

Interventional Cardiologist - 3952 Job at Med Source Consultants

Interventional Cardiologist 3952 Short Drive to Montgomery * Take over thriving practice when longtime Cardiologist retires (2-3yrs)* MGMA median+ Superb quarterly bonus potential * Possible signing bonus, up to $50K, up to $12K for relocation * Full benefits...

Reidy Law Office LLC

Family Law Paralegal Job at Reidy Law Office LLC

 ...opportunities for bonusesLocation: Orland Park, IL (hybrid primarily in-office with some flexibility) (South Chicago Suburbs)Are you a paralegal with a passion for family law and a knack for discovery? Whether youre early in your career or bring years of experience, you... 

State of Indiana

Dealing Resulting in Death Deputy Prosecutor Job at State of Indiana

 ...by Prosecutor Ryan Mears, is setting new expectations in the criminal justice system and is committed to a fair and equitable system. The...  ...at $76,500.00but may be commensurate with education or work experience. Qualified candidates should submit a resume and cover...